About CALERIE
CALERIE Organization
CALERIE's organization consists of three research sites, The National Institute on Aging (an Institute of the National Institutes of Health), the Coordinating Center and the Data and Safety Monitoring Board.
View map of CALERIE sites, sponsor and coordinating center.
Sites
The three sites that are participating in the CALERIE trial represent a diversity of subject populations and interventional strategies. The three CALERIE sites include:
- Pennington Biomedical Research Center (Baton Rouge, LA)
- Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University (Boston, MA)
- Washington University in St. Louis, School of Medicine (St. Louis, MO)
NIA Program Office
The National Institute on Aging (NIA) provides administrative management to the overall CALERIE Program.
Coordinating Center
Duke Clinical Research Institute (DCRI) is serving as the trial's Clinical and Data Coordinating Center. The DCRI has responsibility for implementing and participating in CALERIE processes, involved in CALERIE-wide decisions, development of the multi-center protocol, manual of procedures, site management, clinical monitoring, data management, reporting of data, and participation in data analysis.
Data and Safety Monitoring Board (DSMB)
The CALERIE DSMB is comprised of experts with relevant medical, behavioral, clinical trials and statistical backgrounds. The purpose of the DSMB is to function as an advisory committee to the CALERIE study and the NIA by periodically reviewing the sites-progress and monitoring data integrity and subject safety.